000			01945 a2200253 4500
999			_c2590 _d2590
005			20240920125149.0
008			240920b ||||| |||| 00| 0 eng d
020			_a9781782624479
041			_aeng
082			_a616.07 PIE/C
100			_aPierre, Valerie C _99761
100			_aAllen, Matthew J _99762
245			_aContrast agents for MRI: Experimental methods
260			_bRSC -- _c2017 _aUnited Kingdom --
500			_a*General synthetic and physical methods; *Gadolinium-based contrast agents; *Chemical exchange saturation transfer (CEST) contrast agents; *Iron oxide nanoparticle-based contrast agents; *Transition metal-based T1 contrast agents; *Fluorine-based contrast agents; *Standard biological and in vivo methods
520			_a As a practical reference guide for designing and performing experiments, this book focuses on the five most common classes of contrast agents for MRI namely gadolinium complexes, chemical exchange saturation transfer agents, iron oxide nanoparticles, manganese complexes and fluorine contrast agents. It describes how to characterize and evaluate them and for each class, a description of the theory behind their mechanisms is discussed briefly to orient the new reader. Detailed subchapters discuss the different physical chemistry methods used to characterize them in terms of their efficacy, safety and in vivo behavior. Important consideration is also given to the different physical properties that affect the performance of the contrast agents. The editors and contributors are at the forefront of research in the field of MRI contrast agents and this unique, cutting edge book is a timely addition to the literature in this area.
650			_aMedicine and health _98338
650			_aPathology _99763
650			_aContrast Media _99764
650			_aMagnetic Resonance Imaging methods _99765
650			_aMRI _99766
650			_aDiseases _98978
942			_cBK